ARG22357
anti-pan FGFA / FHFA antibody [S235-22]
anti-pan FGFA / FHFA antibody [S235-22] for ICC/IF,Western blot and Human,Rat
Overview
| Product Description | Mouse Monoclonal antibody [S235-22] recognizes pan FGFA / FHFA |
|---|---|
| Tested Reactivity | Hu, Rat |
| Predict Reactivity | Ms |
| Tested Application | ICC/IF, WB |
| Specificity | Does not cross-react with FGF13B / FHF2B. Cross reacts with FGF12A / FHF1A and FGF14A / FHF4A. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | S235-22 |
| Isotype | IgG2b |
| Target Name | pan FGFA / FHFA |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around aa. 2-18 of Human FHF2A (AAAIASSLIRQKRQARE). 100% identical to Rat, 94% identical to Mouse. > 80% identity with FGF12A/FHF1A, FGF14A/FHF4A and FGF11A/FHF3A. |
| Conjugation | Un-conjugated |
| Alternate Names | FHF-2; FHF2; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; FGF-13; FGF2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 0.1% Sodium azide and 50% Glycerol. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FGF13 |
| Gene Full Name | fibroblast growth factor 13 |
| Background | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008] |
| Function | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. May regulate voltage-gated sodium channels transport and function. May also play a role in MAPK signaling. [UniProt] |
| Calculated MW | 28 kDa |
| PTM | May be phosphorylated. |
