ARG83636
Human Tau phospho (Thr231) ELISA Kit
Human Tau phospho (Thr231) ELISA Kit for ELISA and Human
Neuroscience antibody; Signaling Transduction antibody; Neuron Development Study antibody
Overview
| Product Description | ARG83636 Human Tau phospho (Thr231) ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Tau phospho (Thr231) in CSF, serum and plasma. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | Tau |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 7.8 pg/ml |
| Sample Type | CSF, serum and plasma. |
| Standard Range | 15.625 - 1000 pg/ml |
| Sample Volume | 50 µl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | TAU; Neurofibrillary tangle protein; Paired helical filament-tau; PPND; DDPAC; FTDP-17; MTBT2; Microtubule-associated protein tau; PHF-tau; MSTD; PPP1R103; MTBT1; MAPTL |
Application Instructions
| Assay Time | 4 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P10636 Human Microtubule-associated protein tau |
|---|---|
| Gene Symbol | MAPT |
| Gene Full Name | microtubule-associated protein tau |
| Background | This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008] |
| Function | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt] |
| Highlight | Related products: Tau antibodies; Tau ELISA Kits; Tau Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: "Pro-aging factor" tied to immune-related molecule |
| Research Area | Neuroscience antibody; Signaling Transduction antibody; Neuron Development Study antibody |
Images (1) Click the Picture to Zoom In
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ARG83636 Human Tau phospho (Thr231) ELISA Kit standard curve image
ARG83636 Human Tau phospho (Thr231) ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83636 Human Tau phospho (Thr231) ELISA Kit User manual |
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