ARG70594
Mouse CD56 / NCAM recombinant protein (Active) (His-tagged, C-ter)
Mouse CD56 / NCAM recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
Developmental Biology antibody; Neuroscience antibody; General Lymphocyte Marker Study antibody; Natural killer cells antibody
Overview
| Product Description | CHO expressed, His-tagged (C-ter) Active Mouse CD56 / NCAM recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CD56 / NCAM |
| Species | Mouse |
| A.A. Sequence | Leu20 - Thr711 |
| Expression System | CHO |
| Activity | Active |
| Activity Note | Determined by its ability to support the adhesion of SHSY5Y human neuroblastoma cells, with the ED50 being < 15 μg/mL. |
| Alternate Names | NCAM1; CD56; NCAM; CD antigen CD56; N-CAM-1; MSK39; NCAM-1; Neural cell adhesion molecule 1 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | NCAM1 |
|---|---|
| Gene Full Name | neural cell adhesion molecule 1 |
| Background | This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011] |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. [UniProt] |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Isoform 3: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 4: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 5: Secreted. Isoform 6: Secreted. [UniProt] |
| Highlight | Related products: CD56 antibodies; CD56 ELISA Kits; CD56 Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: Tumor-Infiltrating Lymphocytes (TILs) |
| Research Area | Developmental Biology antibody; Neuroscience antibody; General Lymphocyte Marker Study antibody; Natural killer cells antibody |
| PTM | Disulfide bond; Glycoprotein; GPI-anchor; Lipoprotein; Phosphoprotein. [UniProt] |
