ARG23720
anti-AMBRA1 antibody
anti-AMBRA1 antibody for ICC/IF and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AMBRA1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AMBRA1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around aa. 202-212 of Human AMBRA1. |
| Conjugation | Un-conjugated |
| Alternate Names | DCAF3; Activating molecule in BECN1-regulated autophagy protein 1; WDR94 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.09% Sodium azide and 50% Glycerol. |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9C0C7 Human Activating molecule in BECN1-regulated autophagy protein 1 |
|---|---|
| Gene Symbol | AMBRA1 |
| Gene Full Name | autophagy/beclin-1 regulator 1 |
| Function | Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity). [UniProt] |
| Cellular Localization | Autophagosome. Note: Localizes also to discrete punctae along the ciliary axoneme. [UniProt] |
| Calculated MW | 143 kDa |
Images (1) Click the Picture to Zoom In
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ARG23720 anti-AMBRA1 antibody ICC/IF image
Immunofluorescence: SK-N-BE cells fixed with 4% Formaldehyde for 15 min at RT. Cells were stained with ARG23720 anti-AMBRA1 antibody at 1:100 for 60 min at RT. Magnification: 60X. (A) DAPI (blue) nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) Primary antibodies. (D) Composite.
