ARG54459
anti-BRD2 antibody
anti-BRD2 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes BRD2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | This antibody reacts with human BRD2. The specific epitope is in the region between aa 550 and 600 of human BRD2. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Rhesus Monkey, Gorilla, White-tufted-ear marmoset, Crab-eating macaque and Northern white-cheeked gibbon. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BRD2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide representing a portion of the protein between the putative nuclear localization signal and the ET domain |
| Conjugation | Un-conjugated |
| Alternate Names | O27.1.1; FSH; RING3; D6S113E; FSRG1; Really interesting new gene 3 protein; NAT; Bromodomain-containing protein 2; RNF3 |
Application Instructions
| Predict Reactivity Note | Bovine, Rhesus Monkey, Gorilla, White-tufted-ear marmoset, Crab-eating macaque and Northern white-cheeked gibbon. | ||||
|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity-purified with an epitope specific to BRD2 immobilized on solid support. |
| Buffer | Tris-citrate/phosphate (pH 7-8) and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BRD2 |
| Gene Full Name | bromodomain containing 2 |
| Background | BRD2 (bromodomain-containing 2) is a nuclear mitogen-activated kinase that plays a role in transcription of cell-cycle-regulated genes by functioning as an adapter protein that recruits E2F and chromatin remodeling factors to E2F response elements. |
| Function | May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody |
| Calculated MW | 88 kDa |
Images (1) Click the Picture to Zoom In
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ARG54459 anti-BRD2 antibody WB image
Western Blot: 10ug of HeLa cells untreated (-) or treated (+) with calf intestinal phosphatase stained with ARG54459 anti-BRD2 antibody at 0.05ug/ml dilution.
