ARG59936
anti-CANT1 antibody
anti-CANT1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CANT1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CANT1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 102-401 of Human CANT1 (NP_001153245.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Apyrase homolog; Soluble calcium-activated nucleotidase 1; EC 3.6.1.6; Putative MAPK-activating protein PM09; DBQD; SHAPY; Putative NF-kappa-B-activating protein 107; SCAN-1; SCAN1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | U-251MG | ||||
| Observed Size | 45 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8WVQ1 Human Soluble calcium-activated nucleotidase 1 |
|---|---|
| Gene Symbol | CANT1 |
| Gene Full Name | calcium activated nucleotidase 1 |
| Background | This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010] |
| Function | Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis. [UniProt] |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cell membrane. Note=Processed form: Secreted. [UniProt] |
| Calculated MW | 45 kDa |
| PTM | N-glycosylated. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG59936 anti-CANT1 antibody WB image
Western blot: 25 µg of U-251MG cell lysate stained with ARG59936 anti-CANT1 antibody at 1:1000 dilution.
