ARG56242
anti-CAPG antibody
anti-CAPG antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CAPG |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CAPG |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human CAPG |
| Conjugation | Un-conjugated |
| Alternate Names | AFCP; Macrophage-capping protein; HEL-S-66; Actin regulatory protein CAP-G; MCP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Mouse lung and HL60 |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CAPG |
| Gene Full Name | capping protein (actin filament), gelsolin-like |
| Background | This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012] |
| Function | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. [UniProt] |
| Calculated MW | 38 kDa |
| PTM | The N-terminus is blocked. |
Images (2) Click the Picture to Zoom In
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ARG56242 anti-CAPG antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung cancer stained with ARG56242 anti-CAPG antibody at 1:100 dilution.
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ARG56242 anti-CAPG antibody WB image
Western blot: Mouse lung and HL60 cell lysates stained with ARG56242 anti-CAPG antibody.
