ARG54668
anti-CD150 / SLAM antibody
anti-CD150 / SLAM antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Developmental Biology antibody; Immune System antibody; Microbiology and Infectious Disease antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD150 / SLAM |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, ICC/IF, IHC-P, WB |
| Specificity | Two isoforms of SLAMF1 are known to exist; this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD150 / SLAM |
| Immunogen | Synthetic peptide (15 aa) within aa. 30-80 of Human SLAMF1. |
| Conjugation | Un-conjugated |
| Alternate Names | Signaling lymphocytic activation molecule; IPO-3; CD150; SLAM; CDw150; CD antigen CD150 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Positive Control | Rat Colon Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q13291 Human Signaling lymphocytic activation molecule Swiss-port # Q9QUM4 Mouse Signaling lymphocytic activation molecule |
|---|---|
| Gene Symbol | SLAMF1 |
| Gene Full Name | signaling lymphocytic activation molecule family member 1 |
| Background | SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP). | |
| Research Area | Developmental Biology antibody; Immune System antibody; Microbiology and Infectious Disease antibody |
| Calculated MW | 37 kDa |
| PTM | Phosphorylated on tyrosine residues by FYN. |
Images (3) Click the Picture to Zoom In
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ARG54668 anti-CD150 / SLAM antibody ICC/IF image
Immunofluorescence: Human colon tissue stained with ARG54668 anti-CD150 / SLAM antibody at 20 μg/ml.
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ARG54668 anti-CD150 / SLAM antibody IHC image
Immunohistochemistry: Human colon tissue stained with ARG54668 anti-CD150 / SLAM antibody at 5 μg/ml.
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ARG54668 anti-CD150 / SLAM antibody WB image
Western blot: Rat colon tissue lysate stained with ARG54668 anti-CD150 / SLAM antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
