ARG22553
anti-CD62P / P-Selectin antibody [Psel.KO.2.7]
anti-CD62P / P-Selectin antibody [Psel.KO.2.7] for Flow cytometry,IHC-Frozen sections,Immunoprecipitation and Human,Mouse,Rat,Bovine,Cat,Goat,Horse,Sheep
Overview
| Product Description | Mouse Monoclonal antibody [Psel.KO.2.7] recognizes CD62P / P-Selectin This antibody recognizes human P-Selectin. CD62P is a ~140 kDa surface antigen expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Bov, Cat, Goat, Hrs, Sheep |
| Tested Application | FACS, IHC-Fr, IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Psel.KO.2.7 |
| Isotype | IgG1 |
| Target Name | CD62P / P-Selectin |
| Antigen Species | Human |
| Immunogen | P-selectin transfected 300.19 cells. |
| Conjugation | Un-conjugated |
| Alternate Names | PADGEM; Platelet activation dependent granule-external membrane protein; CD62 antigen-like family member P; Granule membrane protein 140; CD antigen CD62P; Leukocyte-endothelial cell adhesion molecule 3; GMP-140; P-selectin; LECAM3 |
Application Instructions
| Application Suggestion |
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| Application Note | FACS: Use 10ul of the suggested working dilution to label 10^6 cells in 100ul. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SELP |
| Gene Full Name | selectin P (granule membrane protein 140kDa, antigen CD62) |
| Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1 (By similarity). [UniProt] |
| Calculated MW | ~ 140 kDa |
Images (2) Click the Picture to Zoom In
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ARG22553 anti-CD62P / P-Selectin antibody [Psel.KO.2.7] FACS image
Flow Cytometry: thrombin activated Human platelets stained with ARG22553 anti-CD62P / P-Selectin antibody [Psel.KO.2.7].
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ARG22553 anti-CD62P / P-Selectin antibody [Psel.KO.2.7] FACS image
Flow Cytometry: Thrombin activated Dog platelets stained with ARG22553 anti-CD62P / P-Selectin antibody [Psel.KO.2.7] followed by goat anti Mouse IgG (FITC).
