ARG55615
anti-CRTAP antibody
anti-CRTAP antibody for ICC/IF,Western blot and Human
Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CRTAP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CRTAP |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 31-59 (N-terminus) of Human CRTAP. |
| Conjugation | Un-conjugated |
| Alternate Names | OI7; Cartilage-associated protein; P3H5; LEPREL3; CASP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | HT-1080 |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CRTAP |
| Gene Full Name | cartilage associated protein |
| Background | The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass. [provided by RefSeq, Jul 2008] |
| Function | Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 47 kDa |
Images (2) Click the Picture to Zoom In
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ARG55615 anti-CRTAP antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG55615 anti-CRTAP antibody (green) at 1:25 dilution. Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
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ARG55615 anti-CRTAP antibody WB image
Western blot: 35 µg of HT-1080 cell lysate stained with ARG55615 anti-CRTAP antibody at 1:1000 dilution.
