ARG54452
anti-Cytochrome P450 2E1 antibody
anti-Cytochrome P450 2E1 antibody for Western blot and Human,Mouse,Rat,Dog,Guinea pig,Horse,Monkey,Rabbit
Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Cytochrome P450 2E1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Dog, Gpig, Hrs, Mk, Rb |
| Tested Application | WB |
| Specificity | This antibody recognizes human, mouse, rat, rabbit, canine, guinea pig, horse and monkey cytochrome P450 2E1. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Cytochrome P450 2E1 |
| Antigen Species | Rat |
| Immunogen | Native Rat cytochrome P450 2E1 |
| Conjugation | Un-conjugated |
| Alternate Names | EC 1.14.13.n7; Cytochrome P450 2E1; Cytochrome P450-J; EC 1.14.13.-; P450C2E; CYPIIE1; CYP2E; 4-nitrophenol 2-hydroxylase; P450-J; CPE1 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Human, Mouse and Rat liver microsome extract |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A-purified |
| Buffer | PBS, 0.09% Sodium azide and 50% Glycerol |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Cyp2e1 |
| Gene Full Name | cytochrome P450, family 2, subfamily e, polypeptide 1 |
| Background | Cytochrome P450 is a highly conserved, diverse family of heme-containing proteins that function in the metabolism of numerous endogenous and exogenous substrates: organic solvents, acetaminophen, dimethylnitrosamine, aliphatic alcohols, and other potentially toxic compounds for humans.Cytochrome P450 is found mainly in liver but also is found in other organs. It is primarily localized to the inner membranes of mitochondria and the endoplasmic reticulum. Eukaryotic microsomal cytochrome P450 enzymes accept electrons from the FAD- and FMN-containing enzyme NADPH:cytochrome P450 reductase. |
| Function | Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 57 kDa |
Images (1) Click the Picture to Zoom In
-
ARG54452 anti-Cytochrome P450 2E1 antibody WB image
Western blot: 2) Human liver microsomes, 3) Rat liver microsomes, 4) Mouse liver microsomes, and 5) Rabbit liver microsomes stained with ARG54452 anti-Cytochrome P450 2E1 antibody at 2 μg/ml dilution.
