ARG58937
anti-GPR6 antibody
anti-GPR6 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GPR6 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GPR6 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the N-terminal region of Human GPR6. (within the following region: NASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGAN) |
| Conjugation | Un-conjugated |
| Alternate Names | G-protein coupled receptor 6; Sphingosine 1-phosphate receptor GPR6 |
Application Instructions
| Predict Reactivity Note | Predicted Homology Based On Immunogen Sequence: Cow: 86%; Mouse: 93%; Rat: 93% | ||||||
|---|---|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Human placenta |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| Preservative | 0.09% (w/v) Sodium azide |
| Stabilizer | 2% Sucrose |
| Concentration | Batch dependent: 0.5 - 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GPR6 |
| Gene Full Name | G protein-coupled receptor 6 |
| Function | Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Note=Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor. [UniProt] |
| Calculated MW | 38 kDa |
Images (2) Click the Picture to Zoom In
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ARG58937 anti-GPR6 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human placenta stained with ARG58937 anti-GPR6 antibody at 5 µg/ml dilution.
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ARG58937 anti-GPR6 antibody WB image
Western blot: Human placenta lysate stained with ARG58937 anti-GPR6 antibody at 0.2 - 1 µg/ml dilution.
