ARG54647
anti-IL22 antibody
anti-IL22 antibody for ELISA,ICC/IF,Western blot and Human,Mouse,Rat
Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IL22 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IL22 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide (17 aa) within aa. 90-140 of Human IL-22 protein. |
| Conjugation | Un-conjugated |
| Alternate Names | Interleukin-22; zcyto18; IL-TIF; IL-22; IL-21; IL-D110; TIFa; ILTIF; TIFIL-23; IL-10-related T-cell-derived-inducible factor; Cytokine Zcyto18 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HeLa Cell Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Immunogen affinity purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | IL22 |
| Gene Full Name | interleukin 22 |
| Background | Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation (1). Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells (2). IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles (3). |
| Research Area | Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 20 kDa |
Images (3) Click the Picture to Zoom In
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ARG54647 anti-IL22 antibody ICC/IF image
Immunocytochemistry: IL-22 in HeLa cells stained with ARG54647 anti-IL22 antibody at 5 μg/ml.
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ARG54647 anti-IL22 antibody ICC/IF image
Immunofluorescence: IL-22 in HeLa cells stained with ARG54647 anti-IL22 antibody at 20 μg/mL.
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ARG54647 anti-IL22 antibody WB image
Western blot: (A) IL-22 in HeLa cell lysate without blocking peptide (B) IL-22 in HeLa cell lysate with blocking peptide stained with ARG54647 anti-IL22 antibody at 1 μg/ml.
