ARG66360
anti-KHK (isoform A) antibody
anti-KHK (isoform A) antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes KHK (isoform A) |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Specificity | The antibody detects endogenous level of total KHK Isoform A protein. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KHK (isoform A) |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around aa. 90-95 (TTGSV) of Human KHK (isoform A). |
| Conjugation | Un-conjugated |
| Alternate Names | Hepatic fructokinase; Ketohexokinase; EC 2.7.1.3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KHK |
| Gene Full Name | ketohexokinase (fructokinase) |
| Background | This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate. [UniProt] |
| Calculated MW | 33 kDa |
Images (2) Click the Picture to Zoom In
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ARG66360 anti-KHK (isoform A) antibody IHC-P image
Immunohistochemistry: Paraffin-embedded tumors derived from Huh-7 cells stained with ARG66360 anti-KHK (isoform A) antibody (left), or the same antibody pre-incubated with KHK-A aa. 72-115 peptide (right).
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ARG66360 anti-KHK (isoform A) antibody WB image
Western blot: Hepatocytee, Hep3B and Huh7 cell lysates stained with ARG66360 anti-KHK (isoform A) antibody (upper panel) and ARG66361 anti-KHK (isoform C) antibody (lower panel).
