ARG30315

Brain Injury IHC Marker Antibody Duo (GFAP, MMP9)

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Component

Cat No Component Name Host clonality Reactivity Application Package
ARG22191 anti-MMP9 antibody [SB15c] Mouse mAb Hu ELISA, ICC/IF, IHC-P, WB 50 μg
ARG10122 anti-GFAP antibody [GF5] Mouse mAb Hu, Ms, Rat ELISA, ICC/IF, IHC-Fr, WB 50 μg

Overview

Product Description Glial fibrillary acidic protein (GFAP) is the major intermediate filament protein in mature astrocytes, a main type of glial cells in the central nervous system (CNS). GFAP is augmented in astrogliosis, a pathophysiology associated with degenerative and infectious/inflammatory brain disorders.

Matrix metalloproteinase 9 (MMP-9) is a member of metalloproteinases family. It cleaves ECM and cell surface receptors allowing for synaptic and circuit level reorganization. MMP-9 level is increased after traumatic brain injury and involved in the following excitotoxic neuronal loss.

arigo's ARG30292 Brain Injury IHC Marker Antibody Duo (GFAP, MMP9) comprise two antibodies against GFAP and MMP9, the pathological hallmark of CNS lesions, and is excellent for histological analysis of brain injury.

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Target Name Brain Injury IHC Marker
Alternate Names Brain Injury IHC Marker antibody; GFAP antibody; MMP9 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Specific References

Effects of Chronic Restraint Stress on Apoptosis of Amygdala Cells in Rats

ARG10122: IHC-P / Rat

Li-Ru Dong et al.
Fa Yi Xue Za Zhi.,  (2022)

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SCM-198 Alleviates Endometriosis by Suppressing Estrogen-ERα mediated Differentiation and Function of CD4+CD25+ Regulatory T Cells

ARG10122: WB / Mouse

Yun-Yun Li et al.
Int J Biol Sci,  (2022)

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Secreted Neutrophil Gelatinase-Associated Lipocalin Shows Stronger Ability to Inhibit Cyst Enlargement of ADPKD Cells Compared with Nonsecreted Form

ARG10122: WB / Mouse

Hsin-Yin Chuang et al.
Cells.,  (2022)

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SCM-198 Prevents Endometriosis By Reversing Low Autophagy Levels Of Endometriotic Stromal Cells Via Inhibiting TNF-Α-Aromatase-Estrogen-Erα Pathway And Promoting PR Expression

ARG10122: WB / Human

Yikong Lin et al.
Research Square,  (2022)

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RIP3/MLKL pathway-regulated necroptosis: A new mechanism of paclitaxel-induced peripheral neuropathy

ARG10122: IHC-Fr / Rat

Dongyang Ma et al.
J Biochem Mol Toxicol.,  (2021)

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SCM-198 ameliorates endometrial inflammation via suppressing the LPS-JNK-cJUN/cFOS-TLR4-NF-κB pathway

ARG10122: WB / Human

Yikong Lin et al.
Acta Biochim Biophys Sin. (Shanghai),  (2021)

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Hyperbaric Oxygen Therapy Attenuates Burn-Induced Denervated Muscle Atrophy

ARG10122: IHC-Fr / Rat

Chin-An Chen et al.
Int J Med Sci.,  (2021)

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Mechanisms of bupivacaine inhibition of glutamate-induced intracellular calcium elevation in primary cultured rat hippocampal astrocytes.

ARG10122: ICC/IF / Rat

Huan-huan Ma et al.
药学学报,  (2020)

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Hsa_circ_0091074 regulates TAZ expression via microRNA‑1297 in triple negative breast cancer cells.

ARG22191 / 

Hu Jiashu et al.
International Journal of Oncology.,  (2020)

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Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.

ARG10122: WB, IF, IHC-Fr / Rat

Luo Zhenzhao et al.
Cell Mol Neurobiol.,  (2019)

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