ARG30271

Mitochondrial Marker Antibody Panel (Cytochrome C, COX4, HSP60)

publication_link Publication2

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG54173 anti-Hsp 60 antibody Mouse mAb Hu, Ms, Rat ICC/IF, IP, WB 50 μl
ARG54003 anti-COX4 antibody Mouse mAb Goat, Hm, Hu, Mk, Ms, Rat FACS, ICC/IF, IHC-P, IP, WB 50 μl
ARG62461 anti-Cytochrome C antibody [6H2.B4] Mouse mAb Hu, Ms, Rat FACS, ICC/IF, IP, WB 250 μl
ARG65350 Goat anti-Mouse IgG antibody (HRP) Goat pAb Ms ELISA, IHC-P, WB 50 μl

Overview

Product Description

Cytochrome C, COX IV and HSP60 are markers for mitochondrial organelle. Cytochrome C is a component of the electron transport chain in mitochondria. The heme group of Cytochrome C accepts electrons from the b-c1 complex and transfers electrons to the cytochrome oxidase complex. HSP60 is a member of chaperon family. It is essential for the folding and assembly of newly imported proteins in the mitochondria. COX IV is one of the subunit of the Cytochrome C Oxidase (COX) hetero-oligomeric enzyme located in the inner mitochondrial membrane. It helps catalyzing the reduction of molecular oxygen to water coupled to the translocation of protons across inner membrane of mitochondria to drive ATP synthesis.

Nishikimi et al. Nucleic Acids Res 16: 3577 (1988)
Venner et al. DNA Cell Ciol 9: 545-552 (1990)
Kadenbach et al. Free Radic Biol Med 29: 211-221 (2000)

Target Name Mitochondrial Marker
Alternate Names Mitochondrial Marker antibody; COX4 antibody; Hsp 60 antibody; Cytochrome C antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Specific References

KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway

ARG65350: WB / 

Yi-Qing Guo et al.
Biomedicines.,  (2023)

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RSV replication is promoted by autophagy-mediated inhibition of apoptosis.

ARG54173: WB / Human

Li Miao et al.
J Virol.,  (2018)

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