ARG30205
NFkB Activation Antibody Panel
Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody
Publication13
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG51780 | anti-IKK beta phospho (Tyr199) antibody | Rabbit pAb | Hu, Ms, Rat | ICC/IF | 50 μl |
| ARG54059 | anti-IkB alpha antibody (N-term) | Mouse mAb | Hu, Ms, Rat | WB | 50 μl |
| ARG51850 | anti-p38 MAPK phospho (Thr180 / Tyr182) antibody | Rabbit pAb | Hu, Ms, Rat | WB | 50 μl |
| ARG51807 | anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody | Rabbit pAb | Hu, Ms, Rat | ICC/IF, WB | 50 μl |
| ARG51651 | anti-IKB alpha phospho (Ser32 / Ser36) antibody | Rabbit pAb | Hu, Ms, Rat | ICC/IF, IHC-P, WB | 50 μl |
| ARG65351 | Goat anti-Rabbit IgG antibody (HRP) | Goat pAb | Rb | ELISA, IHC-P, WB | 50 μl |
Overview
| Product Description | Rel or NF-kappaB (NF-kB) proteins comprise a family of structurally-related eukaryotic transcription factors that are involved in the control of a large number of normal cellular and organismal processes, such as immune and inflammatory responses, developmental processes, cellular growth, and apoptosis. Up-regulation of phospho-IKK, phospho-p38, phospho-JNK down-regulation of IkB alpha is often associated with the activation of NF-kB downstream signaling pathway. Hayden and Ghosh. (2012) Genes and Dev 26: 203-234 Baeuerle and Henkel. (1994) Ann Rev Immunol 12: 141-179 Related news: Treatment of Obesity with Celastrol Tumor microenvironments are shown to affect progression of several cancer subtypes Immune signaling protein TLR4 has opposing roles in breast cancer development |
|---|---|
| Target Name | NFkB Activation |
| Alternate Names | NFkB Activation antibody; IKB alpha phospho (Ser32 / Ser36) antibody; IKK beta phospho (Tyr199) antibody; SAPK / JNK phospho (Thr183 (221) + Tyr185 (223)) antibody; p38 MAPK phospho (Thr180 / Tyr182) antibody; IkB alpha antibody (N-term) |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Antibody Panel for NFkB Activation |
|---|---|
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody |
Specific References
Angiotensin II Induces Cardiac Edema and Hypertrophic Remodeling through Lymphatic-Dependent Mechanisms
ARG51850: WB / Mouse
DHPA Protects SH-SY5Y Cells from Oxidative Stress-Induced Apoptosis via Mitochondria Apoptosis and the Keap1/Nrf2/HO-1 Signaling Pathway
ARG51850: WB / Human
Downregulation of lncRNA NEAT1 alleviates sepsis-induced acute kidney injury
ARG51651, ARG54059: WB / Human
Kaempferol-Driven Inhibition of Listeriolysin O Pore Formation and Inflammation Suppresses Listeria monocytogenes Infection
ARG51807: WB / Mouse
Cobalt protoporphyrin promotes human keratinocyte migration under hyperglycemic conditions
ARG51850: WB / Human
Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells
ARG51850: WB / Human
Simvastatin Enhances the Chondrogenesis But Not the Osteogenesis of Adipose-Derived Stem Cells in a Hyaluronan Microenvironment.
ARG51807: WB / Human
Angiotensin-(1-7) treatment blocks lipopolysaccharide-induced organ damage, platelet dysfunction, and IL-6 and nitric oxide production in rats.
ARG51850: WB / Rat
A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.
ARG51807: WB / Mouse
The fucoidan from sea cucumber Apostichopus japonicus attenuates lipopolysaccharide-challenged liver injury in C57BL/6J mice.
ARG51807: WB / Mouse
The Different Effects of IFN- β and IFN- γ on the Tumor-Suppressive Activity of Human Amniotic Fluid-Derived Mesenchymal Stem Cells
ARG51807, ARG51850: WB / Human
Effects and mechanisms of PSS-loaded nanoparticles on coronary microcirculation dysfunction in streptozotocin-induced diabetic cardiomyopathy rats.
ARG51651, ARG54059: WB / Rat
Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury.
ARG51807: WB / Mouse
