ARG30006
NSC and Astrocyte Marker Antibody Duo (GFAP, Nestin)
Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody
Publication5
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG52312 | anti-GFAP antibody | Rabbit pAb | Cat, Dog, Hu, Ms, Rat | ICC/IF, IHC-P, IHC-Fr, IHC-FoFr , WB | 50 μl |
| ARG52345 | anti-Nestin antibody [4D11] | Mouse mAb | Hu, Ms, Rat | ICC/IF, IHC-Fr, WB | 50 μl |
Overview
| Product Description | Nestin is an intermediate filament protein expressed in dividing cells during the early development stages of nervous system and is utilized as a neural stem cell marker. The neural stem cells loss Nestin expression once the cell fate is determined. Following gliogenesis, Nestin is replaced by cell type-specific intermediate filaments, e.g., GFAP for astrocytes. Glial fibrillary acidic protein (GFAP) is the major intermediate filament protein in mature astrocytes, a main type of glial cells in the central nervous system (CNS). GFAP is used as a marker to distinguish astrocytes from other glial cells during development. arigo’s ARG30006 NSC and Astrocyte Marker Antibody Duo (GFAP, Nestin) is excellent for distinguishing neural stem cells and mature astrocytes. Moreover, as GFAP is also expressed in adult neural progenitors. This antibody duo is also excellent for identification of adult neural progenitors in brain tissue. Related news: Astrocyte-to-neuron conversion for Parkinson's disease treatment |
|---|---|
| Target Name | NSC and Astrocyte Marker |
| Alternate Names | NSC and Astrocyte Marker antibody; GFAP antibody; Nestin antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Antibody Duo for NSC and Astrocyte Marker (GFAP, Nestin) |
|---|---|
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody |
Specific References
Paclitaxel induces cognitive impairment via necroptosis, decreased synaptic plasticity and M1 polarisation of microglia
ARG52312: IHC-Fr / Mouse
Insulin-like growth factor reduced against decabromodiphenyl ether-209-induced neurodevelopmental toxicity in vivo and in vitro
ARG52345: ICC/IF / Rat
Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer's Disease Pathology and Improve Cognitive Deficits.
ARG52345: WB / Human
Transplantation of encapsulated human Leydig-like cells: A novel option for the treatment of testosterone deficiency.
ARG52345: ICC/IF / Human
Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes
ARG52312: IHC-P, IHC-Fr / Mouse
