ARG30211
Phospho Tau Antibody Panel (Total, pS396, pS404)
Immune System antibody; Neuroscience antibody; Signaling Transduction antibody
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG51614 | anti-Tau phospho (Ser404) antibody | Rabbit pAb | Hu, Ms, Rat | ICC/IF, IHC-P, WB | 50 μl |
| ARG51604 | anti-Tau phospho (Ser396) antibody | Rabbit pAb | Hu, Ms, Rat | IHC-P, WB | 50 μl |
| ARG51094 | anti-Tau antibody | Rabbit pAb | Hu, Ms, Rat | WB, IHC-P | 50 μl |
| ARG65351 | Goat anti-Rabbit IgG antibody (HRP) | Goat pAb | Rb | ELISA, IHC-P, WB | 50 μl |
Overview
| Product Description | Tau is a group of neuronal microtubule-associated proteins that are formed by alternative mRNA splicing and accumulate in neurofibrillary tangles in Alzheimer's disease (AD) brain. Tau plays a key role in regulating microtubule dynamics, axonal transport and neurite outgrowth, and all these functions of tau are modulated by site-specific phosphorylation. Phosphorylation of Tau (Isoform Tau-F) at Ser296 and Ser404 sites by Tau Protein Kinase II is responsible for the functional loss of tau-mediated tubulin polymerization in AD. Evans et al. 2000. J Biol Chem 275(32): 24977-83 Stoothoff and Johnson. 2005. Biochem Biophy Acta 1739(2-3): 280-97 |
|---|---|
| Target Name | Tau |
| Alternate Names | Phospho Tau antibody; Tau antibody; Tau phospho (Ser396) antibody; Tau phospho (Ser404) antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Antibody Panel for Phospho Tau (Total, pS396, pS404) |
|---|---|
| Research Area | Immune System antibody; Neuroscience antibody; Signaling Transduction antibody |
