ARG44412
anti-LAP3 antibody
anti-LAP3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LAP3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LAP3 |
| Antigen Species | Human |
| Immunogen | Human LAP3 recombinant protein (aa. sequence: R130-K497). |
| Conjugation | Un-conjugated |
| Alternate Names | LAP3; Leucine Aminopeptidase 3; LAPEP; Peptidase S; PEPS; LAP; Cysteinylglycine-S-Conjugate Dipeptidase; Cytosol Aminopeptidase; Proline Aminopeptidase; Leucyl Aminopeptidase; Prolyl Aminopeptidase |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LAP3 |
| Gene Full Name | Leucine Aminopeptidase 3 |
| Background | Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Located in cytosol; midbody; and nucleoplasm. |
| Function | Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn2+ ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn2+, it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. |
| Cellular Localization | Cytoplasm |
| Calculated MW | 56 kDa |
| PTM | Acetylation, Phosphoprotein |
Images (4) Click the Picture to Zoom In
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ARG44412 anti-LAP3 antibody IHC-P image
Immunohistochemistry: Human ovarian serous adenocarcinoma stained with ARG44412 anti-LAP3 antibody at 2 μg/mL dilution.
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ARG44412 anti-LAP3 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44412 anti-LAP3 antibody at 5 μg/mL dilution.
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ARG44412 anti-LAP3 antibody WB image
Western blot: Rat live stained with ARG44412 anti-LAP3 antibody at 0.5 μg/mL dilution.
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ARG44412 anti-LAP3 antibody WB image
Western blot: Mouse live stained with ARG44412 anti-LAP3 antibody at 0.5 μg/mL dilution.
