ARG42202
anti-MLC1 antibody
anti-MLC1 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MLC1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MLC1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within aa. 300 to the C-terminus of Human MLC1 (NP_055981.1). |
| Conjugation | Un-conjugated |
| Alternate Names | LVM; MLC; VL; Membrane protein MLC1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | SH-SY5Y | ||||
| Observed Size | ~ 47 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MLC1 |
| Gene Full Name | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| Background | The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Function | Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. [UniProt] |
| Cellular Localization | Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum. [UniProt] |
| Calculated MW | 41 kDa |
Images (1) Click the Picture to Zoom In
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ARG42202 anti-MLC1 antibody WB image
Western blot: 25 µg of SH-SY5Y cell lysate stained with ARG42202 anti-MLC1 antibody at 1:3000 dilution.
