ARG30308

Immature B Cell Marker Antibody Panel (CD19, CD20, CD22, IgM Fc) (FACS)

publication_link Publication1

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG23128 anti-CD19 antibody [LE-CD19] Mouse mAb Hu ELISA, FACS, IP, IHC-P, WB 50 μg
ARG62775 anti-CD22 antibody [MEM-01] Mouse mAb Hu, NHuPrm FACS, IP, WB 50 μg
ARG62767 anti-CD20 antibody [MEM-97] Mouse mAb Hu, Bov, Pig FACS, IP 50 μg
ARG63040 Mouse anti-Human IgM (Fc) antibody [CH2] Mouse mAb Hu ELISA, FACS, ICC/IF, WB 50 μg
ARG65350 Goat anti-Mouse IgG antibody (HRP) Goat pAb Ms ELISA, IHC-P, WB 50 μl
ARG65351 Goat anti-Rabbit IgG antibody (HRP) Goat pAb Rb ELISA, IHC-P, WB 50 μl

Overview

Product Description B cell development occurs in the bone marrow and peripheral lymphoid tissues such as spleen. In the bone marrow, pro B Cell, pre B Cell and Immature B Cell develop. During this differentiation, several stages of rearrangement occur at immunoglobulin locus, resulting in the generation and surface expression of different types of receptors, such as pre-B-cell receptor. Different markers are also expressed at the surface of these cells throughout the development of B cell.

Immature B Cells express IgM, CD19, CD20 and CD22 on the surface of the cells.

Arigo has these marker antibodies in the application of Flow Cytometry for the convenience of identifying Immature B Cells in B cell populations.

Cambier et al. Nature Rev Immunology 7: 633-643 (2007)
Alberts et al. Molecular Biology of the Cell: 1367
Parham. The Immune System
Target Name Immature B Cell Marker
Alternate Names Immature B Cell Marker antibody; CD19 antibody; CD20 antibody; CD22 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Specific References

KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway

ARG65350: WB / 

Yi-Qing Guo et al.
Biomedicines.,  (2023)

publication_link

 

hr_line