ARG30309
Polycomb Complexes Antibody Panel (H3K27me3, EZH2, Ring1A, RNF2)
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG54703 | anti-EZH2 antibody | Rabbit pAb | Hu, Ms | FACS, ICC/IF, IHC, WB | 50 μl |
| ARG63505 | anti-RNF2 / RING1B / BAP1 antibody | Goat pAb | Hu | WB | 50 μg |
| ARG51437 | anti-Ring1A antibody | Rabbit pAb | Hu, Ms, Rat | WB | 50 μl |
| ARG51851 | anti-Histone H3 trimethyl (Lys27) antibody | Rabbit pAb | Hu, Ms, Rat | WB, IHC-P, ICC/IF | 50 μl |
| ARG65351 | Goat anti-Rabbit IgG antibody (HRP) | Goat pAb | Rb | ELISA, IHC-P, WB | 50 μl |
| ARG65352 | Donkey anti-Goat IgG antibody (HRP) | Donkey pAb | Goat | ELISA, IHC, WB | 50 μl |
Overview
| Product Description | Polycomb-group (PcG) genes encode chromatin proteins involved in stable and heritable transcriptional silencing. PcG proteins participate in distinct multimeric complexes that deposit, or bind to, specific histone modifications (e.g., H3K27me3) to prevent gene activation and maintain repressed chromatin domains. Ezh2, Ring1A and Ring1B are core components of the mammalian Polycomb system, which regulates cell differentiation during embryonic development and tissue maintenance during adult life. Grossniklaus and Paro. Cold Spring Harb Perspect Biol 3:11 (2014) Rajasekhar and Begemann. Stem Cells 25: 2498-2510 (2007) Chen et al. Am J Transl Res: 4: 364-75 (2012) |
|---|---|
| Target Name | Polycomb Complexes |
| Alternate Names | Polycomb Complexes antibody; Ring1A antibody; Histone H3 trimethyl (Lys27) antibody; EZH2 antibody; RNF2 / RING1B / BAP1 antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
