ARG30310

Endosome, Lysosome, Peroxisome Marker Antibody Panel (Catalase, Caveolin1, Clathrin heavy chain, LAMP1)

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Component

Cat No Component Name Host clonality Reactivity Application Package
ARG57976 anti-Caveolin 1 antibody Rabbit pAb Hu, Ms ICC/IF, IHC-P, WB 50 μl
ARG63969 anti-Catalase antibody Goat pAb Hu, Ms WB, IHC-P 50 μg
ARG52327 anti-CD107a / LAMP1 antibody [5H6] Mouse mAb Bov, Hu ICC/IF, WB 50 μl
ARG53919 anti-CLTC / Clathrin heavy chain antibody [BF-06] Mouse mAb Bov, Hu, Ms, Pig, Rat ELISA, FACS, ICC/IF, IP, WB 50 μg
ARG65350 Goat anti-Mouse IgG antibody (HRP) Goat pAb Ms ELISA, IHC-P, WB 50 μl
ARG65351 Goat anti-Rabbit IgG antibody (HRP) Goat pAb Rb ELISA, IHC-P, WB 50 μl

Overview

Product Description Caveolin-1 (Cav-1) and Clathrin are markers for endosome. Cav-1 is a scaffolding protein within caveolar membranes in a transport vesicle. Clathrin is the major protein of the polyhedral coat of coated pits and vesicles and has a frunction in membrane invagination. The basic Clathrin oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains.

Lysosome-associated membrane glycoprotein 1 (Lamp1) is a marker for lysosome while catalase is a marker for Peroxisome organelle. Lamp1 functions to present carbohydrates to selectins and Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide.

Glenny et al. FEBS Lett 314: 45-48 (1992)
Dodge et al. Genomics 11:174-178 (1991)
Chen et al. J Proteome Res 8: 651-661 (2009)
Target Name Endosome, Lysosome, Peroxisome Marker
Alternate Names Endosome, Lysosome, Peroxisome Marker antibody; CD107a / LAMP1 antibody; CLTC / Clathrin heavy chain antibody; Caveolin 1 antibody; Catalase antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Specific References

KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway

ARG65350: WB / 

Yi-Qing Guo et al.
Biomedicines.,  (2023)

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